Blood tests explained

The Pathhealth
Biomarker Guide.

Understand what common blood tests measure, why they may be useful and when additional testing needs clinical context.

Not a self-ordering menuEvery panel begins with a shared core. Additional tests depend on your intake, age, sex, symptoms, history, medication, risk factors and laboratory availability.
Core

Included in the shared preventative-health foundation.

Expanded

Generally included in broader Pathhealth panels.

Clinically selected

Added only when the intake or risk profile supports it.

Blood health

A full blood count looks at the cells that carry oxygen, support immunity and help blood clot.

Full blood count (FBC / CBC)

Core

Includes haemoglobin, haematocrit, red-cell indices, white-cell count and differential, and platelets.

Kidney function & electrolytes

These markers help assess filtration, hydration and the body’s mineral balance.

Creatinine and estimated GFR

Core

Used together to estimate how effectively the kidneys filter blood.

Urea

Core

Provides additional context about kidney function, hydration and protein metabolism.

Sodium and potassium

Core

Key electrolytes involved in fluid balance, nerves, muscles and heart rhythm.

Chloride and bicarbonate

Expanded

May add context about electrolyte and acid–base balance when available.

Liver function & proteins

No single test measures every aspect of liver health, so results are interpreted as a pattern.

ALT and AST

Core

Enzymes that may rise when liver or other cells are stressed or injured.

Alkaline phosphatase (ALP)

Core

Interpreted alongside other results when considering the liver, bile ducts and bone.

Bilirubin

Core

A pigment processed by the liver; interpretation depends on the result pattern and clinical context.

Albumin and total protein

Core

Provide context about protein balance, liver synthesis and other health factors.

Gamma-GT (GGT)

Expanded

Can help interpret liver and bile-duct enzyme patterns.

Glucose & metabolic health

These tests provide complementary views of current and longer-term glucose regulation.

Fasting glucose

Core

A snapshot of blood glucose after an appropriate fasting period.

HbA1c

Core

Reflects average glucose exposure over roughly the preceding two to three months.

Uric acid

Expanded

May be relevant to gout, kidney health and broader metabolic context.

Fasting insulin

Clinically selected

May occasionally add context, but is not required for routine diabetes screening.

Cholesterol & cardiovascular risk

These markers help build a more complete picture of lipid-related cardiovascular risk.

Total cholesterol, LDL-C, HDL-C and triglycerides

Core

The standard lipid profile, interpreted together rather than as isolated numbers.

Apolipoprotein B (ApoB)

Expanded

Reflects the number of atherogenic lipoprotein particles and can refine risk assessment.

Lipoprotein(a) / Lp(a)

Expanded

A largely inherited risk marker that is generally measured at least once rather than repeatedly.

High-sensitivity CRP (hs-CRP)

Expanded

A non-specific inflammation marker that may refine cardiovascular risk in selected contexts.

Iron & nutritional markers

These tests are most useful when the intake identifies a relevant symptom, dietary pattern or risk factor.

Ferritin and iron studies

Clinically selected

Assess iron stores and transport using ferritin, iron, transferrin or TIBC, and transferrin saturation.

Vitamin B12 and folate

Clinically selected

May help investigate anaemia, neurological symptoms, dietary risk or malabsorption.

25-hydroxy vitamin D

Clinically selected

Used when deficiency risk or a relevant clinical reason is identified; not automatically required for everyone.

Thyroid

Thyroid testing is selected using symptoms, history, medications and risk rather than added automatically.

Thyroid-stimulating hormone (TSH)

Clinically selected

Usually the initial laboratory test when thyroid dysfunction is suspected.

Free T4

Clinically selected

Adds context when TSH is abnormal or the clinical situation warrants it.

Free T3 and thyroid antibodies

Clinically selected

Reserved for specific questions rather than routine inclusion in every panel.

Hormonal health

Hormones vary with symptoms, medication, time of day, menstrual stage and other biological factors.

Total testosterone and SHBG

Clinically selected

May be combined to provide context about androgen status when there is an appropriate indication.

Estradiol, LH and FSH

Clinically selected

Can help answer selected reproductive or endocrine questions when timing and context are recorded.

Prolactin

Clinically selected

Used for particular symptoms or endocrine questions, not as a universal wellness test.

Urine & risk-based screening

Some useful preventive tests are not blood biomarkers and require specific eligibility or consent.

Urine albumin-to-creatinine ratio

Clinically selected

Can detect small amounts of urinary albumin in people with relevant kidney or cardiovascular risk.

PSA

Clinically selected

Requires an informed, age- and risk-appropriate discussion because potential benefits and harms differ.

HIV or hepatitis screening

Clinically selected

Offered only with appropriate eligibility, explanation and consent.

From tests to understanding

A longer list is not automatically a better health assessment.

Pathhealth is designed to select useful tests, preserve their laboratory context and turn the results into a clear report. Final test availability and composition are confirmed during coordination.

Explore health panels →